Welcome to the Biofluids Research Group
Danny Bluestein, Ph.D.
SUNY Distinguished Professor
Biomedical Engineering
Stony Brook University
The focus of the Biofluids Research Group is the study of the dynamics of blood flow and cellular transport in the cardiovascular system, with an emphasis on flow-induced mechanisms underlying cardiovascular disease processes and their progression. Pathological flow fields that arise as a result of cardiovascular diseases or prosthetic devices have a complex interaction with blood vessels and blood itself. Over the last decade, evidence has accumulated indicating that local flow-induced stresses alter the molecular mechanisms of the formed elements of blood, and have a major effect on blood clotting. The end result can be thrombus formation that can occlude arteries, or handicap the functionality of implanted devices such as ventricular assist devices (VADs), total artificial hearts (TAH), and prosthetic heart valves.
BFRG News
![Bluestein headshot](/commcms/bme/bfrg/_images/bluestein.jpg)
Prof. Bluestein Delivers TAVR Keynote Lecture at CMBE24
Prof. Bluestein gave a keynote lecture on BFRG's TAVR work at the 8th International Conference on Computational & Mathematical Biomedical Enginering (CMBE24) at George Mason University, Arlington, Virginia (June 2024).
![SB3C 2024](/commcms/bme/bfrg/_images/SB3C_2024_v2.jpg)
BFRG Attends SB3C in Lake Geneva, Wisconsin
Symon Reza, Kyle Baylous, and Prof. Bluestein represented BFRG at the Summer Biomechanics, Bioengineering, and Biotransport Conference (SB3C) in Lake Geneva, Wisconsin, where Symon was a runner-up in the PhD Student Paper Competition in June 2024
![Brandon NAI award](/commcms/bme/bfrg/_images/BrandonNAI.jpg)
Dr. Brandon Kovarovic receives 2024 Young Academic Inventor Award
Dr. Brandon Kovarovic received a 2024 Young Academic Inventor Award from the SBU chapter of the National Academy of Inventors (NAI) for his inventions directed to artificial polymeric heart valve systems in May 2024
![Salwa Hooding](/commcms/bme/bfrg/_images/SalwaHooding.png)
Dr. Salwa Anam awarded Ph.D. at SBU Doctoral Hooding Ceremony
Dr. Salwa Anam received her Ph.D. degree at the Doctoral Hooding Ceremony during Stony Brook University's 64th Commencement Ceremony in May 2024
![Symon Reza](/commcms/bme/bfrg/_images/symon.jpg)
Symon Reza presents at the SIMULIA Americas Users Conference
Symon Reza presented his work on using the SIMULIA Living Heart Human Model for advancing transcatheter aortic valve replacement technology at the SIMULIA Americas Users Conference in Novi, Michigan in April 2024
![URECA 2024](/commcms/bme/bfrg/_images/URECA.jpg)
Ishani Bansal and Shubh Thaker present research at the URECA Celebration
Ishani Bansal and Shubh Thaker presented highlights of their undergraduate research with BFRG at Stony Brook's Undergraduate Reseach & Creative Activities (URECA) Celebration in April 2024
![Dr. Salwa Anam](/commcms/bme/bfrg/_images/salwa.jpg)
Dr. Salwa Anam successfully defends her PhD dissertation
Dr. Salwa Anam successfully defended her dissertation "Development of Patient-specific In-silico and In-vitro Modeling Framework to Investigate and Mitigate Post-Transcatheter Aortic Valve Replacement Complications in Bicuspid Aortic Valve Patients" in April 2024
![NEBEC 2024](/commcms/bme/bfrg/_images/NEBEC2024_v2.jpg)
Shubh Thaker presents at NEBEC
Shubh Thaker presented deep learning segmentation-guided construction of numerical models from aortic valve CT images of the aortic valve at the 50th Northeast Bioengineering Conference (NEBEC) in Hoboken, New Jersey in April 2024
![OVPR Seed Image](/commcms/bme/bfrg/_images/OVPRSeed.png)
Drs. Sheriff and Bluestein awarded OVPR Seed Grant
Drs. Sheriff and Bluestein, along with collaborators Drs. Bahou and Deng, received an SBU OVPR Seed Grant award in January 2024 for their proposal "Platelet Mechanical Stiffness and Shear-Mediated Response Across the Lifespan"
![CVID conference](/commcms/bme/bfrg/_images/CVID2.png)
Prof. Bluestein and Salwa Anam present at CardioVascular Implant Durability Conference
Prof. Bluestein and Salwa Anam presented BFRG's progress on TAVR valve development and modeling at the CardioVascular Implant Durability (CVID) Conference, held in Pacific Grove, California in October 2023
![BMES 2023 banner](/commcms/bme/bfrg/_images/BMES_2023_banner_cropped.png)
BFRG presents research advances at the 2023 BMES Annual Conference
Kyle Baylous and Symon Reza presented BFRG's recent work on TAVR valve modeling and multiscale platelet adhesion at the 2023 Biomedical Engineering Society Annual Meeting, held in Seattle, Washington in October 2023
![Symon Reza](/commcms/bme/bfrg/_images/symon.jpg)
Symon Reza receives Outstanding Presentation Award at CMU Forum on Biomedical Engineering
Symon Reza was awarded for his presentation on "Computational Biomechanics in the Advancement of Transcatheter Aortic Valve Replacement Technology" at the 5th Carnegie Mellon Forum on Biomedical Engineering in September 2023
![KyleBaylous](/commcms/bme/bfrg/_images/kyle.jpg)
Kyle Baylous wins Faculty Choice Award at Stony Brook BME Research Day
Kyle Baylous received the Faculty Choice Award for Best Podium Presentation at the annual Research Day on his work on design and optimization of novel TAVR devices (August 2023)
![Mount Holyoke College](/commcms/bme/bfrg/_images/mountholyoke_GRC.jpg)
Prof. Bluestein presents multiscale platelet model at Gordon Research Conference 2023
Prof. Bluestein presented recent advances in the AI-enhanced multiscale platelet model at the 2023 Gordon Research Conference on Biomechanics in Vascular Biology and Disease, held at Mount Holyoke College, Massachusetts in August 2023.
![SB3C 2023](/commcms/_resources/images/second-level/about/SB3C_2023.jpeg)
BFRG presents at SB3C 2023
The Biofluids Research Group presented their latest research at the Summer Biomechanics, Bioengineering, and Biotransport Conference held in Vail, Colorado in June 2023
![Ishani Bansal NEBEC 2023](/commcms/_resources/images/second-level/about/IshaniBansal_cropped.png)
Ishani Bansal wins Best Poster Presentation at NEBEC 2023
Ishani Bansal received the Best Poster Presentation Award at the 49th Northeast Bioengineering Conference, held at Drexel University in Philadelphia, Pennsylvania in April 2023
![NEBEC 2023](/commcms/_resources/images/second-level/about/NEBEC2023_1.jpg)
Ishani Bansal presents platelet dynamics at NEBEC 2023
Ishani Bansal presented her research on machine learning-guided platelet flipping dynamics during adhesion at the 49th Northeast Bioengineering Conference in Philadelphia, Pennsylvania in April 2023
![Bluestein SUNY Distinguished Professor](/commcms/_resources/images/second-level/about/Danny%20Bluestein%202023.jpeg)
Dr. Bluestein appointed as SUNY Distinguished Professor
Dr. Bluestein was appointed as Distinguished Professor at the State University of New York in December 2022 and joins the SUNY Distinguished Academy, which leverages the collective contributions of its members to build and support academic excellence within SUNY